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recJ [2017-8-11 16:0:3]
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recJ [2017-8-11 16:0:3]

single-strand DNA-specific exonuclease
Locus
BSU27620
Isoelectric point
5.18
Molecular weight
87.83 kDa
Protein length
786 aa Sequence Blast
Gene length
2358 bp Sequence Blast
Function
DNA repair
Product
single-strand DNA-specific exonuclease
Essential
no
Synonyms
yrvE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Genetics → DNA replication
  • Information processing → Genetics → DNA repair/ recombination → Other proteins
  • Information processing → Genetics → DNA repair/ recombination/ based on similarity
  • Groups of genes → Efp-dependent proteins

    • Gene

    Coordinates
    2,823,419 → 2,825,779

    Phenotypes of a mutant

  • recO recJ double mutants are extremely sensitive against DNA damaging agents PubMed

    • The protein

    Protein family

  • recJ family (according to Swiss-Prot)

    • Paralogous protein(s)

  • YorK

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    recJ-apt
    Description
    PubMed

    Regulatory mechanism

  • stringent response: negative regulation, in stringent response

    • Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed
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    Additional information

  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

    • Biological materials

    Mutant

  • MGNA-B516 (yrvE::erm), available at the NBRP B. subtilis, Japan
  • GP895 (recJ::kan), available in Jörg Stülke's lab
  • BKE27620 (recJ::erm, available in the BGSC, in Fabian Commichau's, and in Jörg Stülke's labs) PubMed

    • References

    Reviews

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    Original publications

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